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Thursday, April 30, 2020 | History

2 edition of Bioassay of 1-nitronaphthalene for possible carcinogenicity. found in the catalog.

Bioassay of 1-nitronaphthalene for possible carcinogenicity.

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Published by Dept. of Health, Education, and Welfare, Public Health Service, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English

  • Carcinogens.,
  • Naphthalene -- Toxicology.,
  • Nitrogen compounds -- Toxicology.

  • Edition Notes

    SeriesCarcinogenesis technical report series ; no. 64, DHEW publication ; no. (NIH) 78-1314, DHEW publication -- no. (NIH) 78-1314.
    The Physical Object
    Paginationix, 46, [58] p. :
    Number of Pages58
    ID Numbers
    Open LibraryOL18013042M

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Bioassay of 1-nitronaphthalene for possible carcinogenicity. by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

Bioassay of 1-nitronaphthalene for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors: National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

OCLC Number: Notes: Spine title: 1-nitronaphthalene. "CAS no. Online book: Additional Physical Format: Print version: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention. Bioassay of 1-nitronaphthalene for possible carcinogenicity (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource: Document Type: Internet Resource.

A bioassay of technical grade 1-nitronaphthalene for possible carcinogenicity was conducted using Fischer rats and B6C3F1 mice. /The cmpd/ was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species.

Bioassay of piperonyl butoxide for possible carcinogenicity Published: () Bioassays of DDT, TDE, and p, p'-DDE for possible carcinogenicity Published: () Bioassay of dixathion for possible carcinogenicity Published: (). The NIH Library is a leading biomedical research library whose collection and services are developed to support the programs of the National Institutes of Health and selected U.S.

Bioassay of 1-nitronaphthalene for possible carcinogenicity. book Department of Health and Human Services (HHS) agencies. This digitized collection of NIH Annual Reports is provided as. 1-Naphthylamine was metabolized to 2-aminonaphthyl monophosphate ester and para-hydroxy conjugates.

1-Naphthylamine and 2-naphthylamine are hydroxylated, but 2-naphthylamine was oxidized to 2-nitrosonaphthalene, showing that this further n-oxidative step does not appear to occur with the more stable nnaphthylhydroxylamine.

Thus the. Unfortunately, this book can't be printed from the OpenBook. If you need to print pages from this book, we recommend downloading it as a PDF. Visit to get more information about this book, to buy it in print, or to download it as a free PDF.

We also performed a separate reevaluation of the NCI/NTP carcinogenicity data for the 25 S. typhimurium "false positives," assuming that the NTP evaluations of. The purpose of this study was to examine whether a simple bioassay used for the detection of dioxins (DXNs) could be applied to detect trace amounts of harmful DXN-like substances in food products.

To identify substances with possible DXN-like activity, we assessed the ability of various compounds in the environment to bind the aryl hydrocarbon receptor (AhR) that binds Cited by: 4.

Naphthalene (CAS Registry Number ; molecular formula C10H8) is a white crystalline powder with a characteristic odour (of mothballs). It is a two-ring aromatic hydrocarbon isolated from coal tar. Synonyms used are antimite, naphthalin, naphthaline, naphthene and tar camphor.

Naphthalene is the most volatile polycyclic aromatic hydrocarbon (PAH) with a gas-phase part. Bioassay of 1-nitronaphthalene for possible carcinogenicity. book 1-Nitronaphthalene [] () 2-Nitronaphthalene [] () This knowledge allows a more sophisticated interpretation of the results of a carcinogenicity bioassay.

Research towards a better understanding of the mechanisms of action of carcinogenicity is encouraged because it may lead to an altered classification and to the. F.R. de Gruijl, H.N. Ananthaswamy, in Comprehensive Toxicology, Immunosuppression.

In addition to the research on UV genotoxicity and carcinogenicity, studies performed since the mids have shown that UV irradiation interferes with an immune defense mechanism that protects unirradiated animals from outgrowths of syngeneic implants of UV.

Winsten JA (eds) Origins of Human Cancer Book C. Cold Spring Harbor Labs, New York pp Use of Short Term Genotoxic Bioassays in the Evaluation of Automotive Emissions () EPA Technical Kenorl sEPA/1 / Available from NT1S, Port Royal Road, Springfield VA « ELSEVIER Mutation Research () Genetic Toxicology QSARS of mutagens and carcinogens: Two case studies illustrating problems in the construction of models for noncongeneric chemicals 1 Romualdo Benigni a,*, Ann M.

Richard b a Laborator3' of ComparatiL,e Toxicology and EcoToxicology, lstituto Superiore di SanitY, Viale Regina Elena Cited by: In this paper, we consider the possible role of nitroarenes as causative compounds for human cancer. At the outset, it is important to recognize that adequate data to answer this question are not available.

However, we will evaluate existing data with respect to three major cancer sites: lung, bladder, and by: 8. The Use of Cell Viability Assay Data Improves the Prediction Accuracy of Conventional Quantitative Structure Activity Relationship Models of Animal Available via.

() also measured the levels of nine nitro-PAHs: 1-nitronaphthalene, 2-methyl-nitronaphthalene, methyl-nitronaphthalene, 9-nitroanthracene, 3-nitrofluoranthene, 1-nitropyrene, 7-nitrobenzo[a]anthracene, 6-nitrochrysene, and 6-nitrobenz[a]pyrene.

The sum of their emission rates, excluding 2-methyl-nitronaphthalene and methyl-nitronaphthalene. Full text of "Report of program activities: National Cancer Institute" See other formats.

The MTD and half the MTD are the usual doses used in the NCI carcinogenicity bioassay. The main reason cited for using the MTD as the highest dose in the bioassay is that experimental studies ere conducted on a small scale, making them "statistically insensitive," and that very high doses overcome this problem.

Mapping Indicators of Toxicity for Polycyclic Aromatic Compounds in the Atmosphere of the Athabasca Oil Sands RegionCited by: The rate consts. of NO3 addn. to 1-nitronaphthalene and 2-nitronaphthalene by RRKM method at K and 1 atm are x and x cm3 mol s-1, resp.

This study provides a comprehensive investigation of the formation process of dinitro-naphthalenes, initiated by OH and NO3 radicals and should facilitate to illuminate its atm.

: Nana Bai, Weihua Wang, Yun Zhao, Wenling Feng, Ping Li. Determination of nitrated polynuclear aromatic hydrocarbons in particulate extracts by using capillary column gas chromatography with nitrogen selective detection. SELECTED POLLUTANTS WHO GUIDELINES FOR INDOOR AIR QUALITY WHO guidelines for indoor air quality: selected pollutants The WHO European Centre for Environment and Health, Bonn Office, WHO Regional Office for Europe coordinated the development of these WHO guidelines.

Keywords AIR POLLUTION, INDOOR - prevention. [] J.K. Haseman, A.-M. Clark, Carcinogenicity results for laboratory animal studies used to assess the predictivity of four in vitro genetic toxicity assays for rodent carcinogenicity, Environ.

ABSTRACT This assessment examined information regarding the possible health hazards associated with exposure to diesel engine exhaust (DE), which is a mixture of gases and particles. The assessment concludes that long-term (i.e., chronic) inhalation exposure is likely to pose a lung cancer hazard to humans, as well as damage the lung in other.

Abstract This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon.

Chapter 33 - Toxicology. INTRODUCTION Ellen K. Silbergeld Toxicology is the study of poisons, or, more comprehensively, the identification and quantification of adverse outcomes associated with exposures to physical agents, chemical substances and other conditions.

As such, toxicology draws upon most of the basic biological sciences, medical disciplines, epidemiology and some. Polycyclic aromatic hydrocarbons-Carcinogenicity. Polycyclic aromatic hydrocarbons-Toxicology. Chemical carcinogenesis. Genetic toxicology.

Luch, Andreas. RCP64C 'dc22 British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. Exploring the direct impacts of particulate matter and surface ozone on global crop production.

NASA Astrophysics Data System (ADS) Schiferl, L. D.; Heald, C. The current era of rising food demand to feed an increasing population along with expansion of industrialization throughout the globe has been accompanied by deteriorating air quality and an enhancement.

Possible outcomes are recovery following cessation of exposure, persistence of changes, or progression to aplastic anaemia, myelodysplastic syndrome, or leukaemia (Rosner and Grunwald ).

Classification of haematotoxicity is generally based on the type of injury or the compartment affected, as shown in Tablerather than the mechanism of.

Figure Postulated reaction scheme for naphthalene with the hydroxyl radical (in the presence of NOx). Note that the OH-naphthalene adduct with the OH adding at the 2-position will also produce 2-naphthol, 1-nitronaphthalene and 2-formylcinnamaldehyde by reactions analogous to those shown for the adduct formed from OH addition at the 1-position.

Categories. Baby & children Computers & electronics Entertainment & hobby. The possible number of hydrocarbon compounds in mineral oil products easily exceeds for those with less than 20 carbon atoms and increases exponentially with the number of carbon atoms, as illustrated in Figure.

Not all possible isomers are present in every product, but the majority are (Beens, ). Free essays, homework help, flashcards, research papers, book reports, term papers, history, science, politics.

present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in .